Her practice includes:
- Diligence opinions
- Educating clients about patent law and case law relating to patents
- Freedom-to-operate analyses
- Global patent portfolio management
- Intellectual property
- Patent preparation
- U.S. and foreign patent prosecution
Nicole’s experience spans the entire pharmaceutical development timeline, from initial filings for the composition of matter and novel chemical entities to second-generation filings. She handles salt forms, prodrugs, polymorph crystal forms, metabolites, formulations, antibody-drug conjugates, combination therapies, dosages and synthetic routes. She also prepares patent applications related to siRNA, oligonucleotides, solid-state electrolytes, enzymatic templates and photoswitches.
Nicole’s research background in medicinal and process chemistry includes work on a multimillion-dollar National Institute of Health (NIH) grant, where she generated a library of glycosphingolipid analogs. These immunostimulatory compounds were investigated for cancer therapies and as vaccine adjuvants. Under the guidance of Dr. Jonathan Reeves, she developed a novel, titanium-free method for generating chiral N-substituted ketimines, which are valuable synthetic intermediates for stereoselectively inducing asymmetry in active pharmaceutical ingredients.
Clients benefit from Nicole’s deep scientific knowledge and practical experience in managing complex intellectual property matters, ensuring comprehensive protection for their innovations.
